Alpha-halocarboxylic acids and derivatives

Cayman Chemical Pentosidine trifluoroacetate

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A well-characterized natural advanced glycation end (AGE) that is often used as a biomarker for the production of all AGEs

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Cayman Chemical Pam2CSK4 trifluoroacetate sa

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A bacterial lipopeptide and TLR2 agonist; selective for TLR2/TLR6 over TLR2/TLR1 (EC50s = 0.015 and 4.12 ng/ml, respectively, in reporter assays using human receptors); increases levels of iNOS and the production of NO in RAW 264.7 macrophages at 100 ng/ml; stimulates osteoclast formation, induces gingival inflammation, and decreases alveolar bone mass in a mouse model of periodontitis at 5 UG/animal; reduces parasite burden and enhances the response to antigen in a mouse model of lymphatic filariasis induced by B. malayi when used as an adjuvant at 10 UG/vaccine

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Sigma Aldrich Fine Chemicals Biosciences Iodoacetic Acid | 64-69-7 |  MFCD00002685 | 100g

Iodoacetic Acid | Purity: 98% | Mol Wt: 185.95 | 64-69-7 |  MFCD00002685 | 100g

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Cayman Chemical MSG606 trifluoroacetate salt

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A peptide MC1R antagonist (IC50 = 17 nM); selectively binds to MC1R over MC3R and MC5R (IC50s = 3,900 and 1,000 nM, respectively), as well as MC4R at 10 µM; increases the latency to tail withdrawal in the tail-flick test in female, but not male, mice in a model of opioid-induced hyperalgesia at 7.5 UG/animal, i.c.v.; reduces protein levels of merlin in the cortex, reduces the number of surviving neurons in the cortex and hippocampal CA2 region, and increases the number of apoptotic cells in the cortex in rats 24 hours after injury in a model of controlled cortical impact-induced TBI at 1 nmol/animal, i.c.v.

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eMolecules​ 79-08-3 | Bromoacetic acid | Chem-Impex138.948 | C2H3BrO2 | 98.000 | OC(=O)CBr | 250g | 112766269

Bromoacetic acid | Chem-Impex | 79-08-3138.948 | C2H3BrO2 | 98.000 | OC(=O)CBr | 250g | 112766269

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Sigma Aldrich Fine Chemicals Biosciences Sodium iodoacetate BioUltra, >=98% | 305-53-3 | MFCD00002686 | 5G

Sodium iodoacetate BioUltra, >=98% | Purity: >=98% | Mol Wt: 207.93 | 305-53-3 | MFCD00002686 | 5G

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eMolecules​ 79-08-3 | Bromoacetic acid | Chem-Impex138.948 | C2H3BrO2 | 98.000 | OC(=O)CBr | 25g | 112766267

Bromoacetic acid | Chem-Impex | 79-08-3138.948 | C2H3BrO2 | 98.000 | OC(=O)CBr | 25g | 112766267

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Sigma Aldrich Fine Chemicals Biosciences Sodium iodoacetate >=98% | 305-53-3 | MFCD00002686 | 100G

Sodium iodoacetate >=98% | Purity: >=98% | Mol Wt: 207.93 | 305-53-3 | MFCD00002686 | 100G

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Cayman Chemical trifluoroacetate salt 5mg

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A derivative of GLP-1

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AdipoGen GE23077 A1 B1

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Chemical. CAS 752989-46-1, 752989-45-0752989-44-9. Formula C31H51N9O16, C31H49N9O16. MW 805.8803.8. Isolated from Actinomadura sp. Cyclic heptapeptide antibiotic. Potent and selective inhibitor of bacterial RNA polymerase RNAP. Inhibits Gram-positive Bacillus subtilis and Gram-negative Escherichia coli RNAPs with IC50 ~20nM, whereas it is not active on E. coli DNA polymerase or on eukaryotic wheat germ RNAP II IC50 values >100µM. Even though of its potent activity in vitro on purified bacterial RNAPs, it shows a narrow spectrum of antimicrobial activity in vivo on Gram-positive and Gram-negative bacteria, due to lack of memmbrane permeability. Acts at the level of transcription initiation. Binds directly to the bacterial RNA polymerase RNAP active-center i and i1 nucleotide binding sites, preventing the binding of initiating nucleotides and thereby preventing transcription initiation.

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eMolecules​ 5292-43-3 | Bromoacetic acid tert-butyl ester | Chem-Impex | MFCD00000188 | 195.056 | C6H11BrO2 | 99.000 | CC(C)(C)OC(=O)CBr | 1kg | 272388277

Bromoacetic acid tert-butyl ester | Chem-Impex | 5292-43-3 | MFCD00000188 | 195.056 | C6H11BrO2 | 99.000 | CC(C)(C)OC(=O)CBr | 1kg | 272388277

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Medchemexpress LLC Guanosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate], sodium salt | 208445-07-2 | 99.9% | 525.86 | 1 MG

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Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. It functions as an inhibitor for cGMP-dependent protein kinase (cGK) and as an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner.

• Inhibits the cGMP-cGKI pathway.
• Suppresses tumor cell implantation-induced thermal hyperalgesia and mechanical allodynia.
• Solid appearance.
• White to off-white color.
• Store at -20°C, sealed, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture).

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eMolecules​ 381-73-7 | Difluoroacetic acid | Oakwood Chemicals | MFCD00004220 | 96.033 | C2H2F2O2 | 97.000 | OC(=O)C(F)F | 100g | 480099410

Difluoroacetic acid | Oakwood Chemicals | 381-73-7 | MFCD00004220 | 96.033 | C2H2F2O2 | 97.000 | OC(=O)C(F)F | 100g | 480099410

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eMolecules​ 10009-70-8 | (R)-(+)-2-Bromopropionic acid | Combi-Blocks | MFCD00145205 | 152.975 | C3H5BrO2 | 96.000 | C[C@@H](Br)C(O)=O | 25g | 296393039

(R)-(+)-2-Bromopropionic acid | Combi-Blocks | 10009-70-8 | MFCD00145205 | 152.975 | C3H5BrO2 | 96.000 | C[C@@H](Br)C(O)=O | 25g | 296393039

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eMolecules​ 1878-67-7 | 2-(3-bromophenyl)acetic acid | Pharmablock | MFCD00004330 | 215.046 | C8H7BrO2 | 97.000 | OC(=O)Cc1cccc(Br)c1 | 500mg | 781214097

2-(3-bromophenyl)acetic acid | Pharmablock | 1878-67-7 | MFCD00004330 | 215.046 | C8H7BrO2 | 97.000 | OC(=O)Cc1cccc(Br)c1 | 500mg | 781214097

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